We also performed this analysis based on proportion of Native American ancestry. Individuals with low (<10%; 3870 cases and 3572 controls) or moderate proportion (10–30%; 255 cases and 131 controls) of Native American ancestry did not show SLE association with rs3765598, Plow = 0.70 and Pmoderate = 0.99 respectively. However, individuals with relatively higher proportions of Native American ancestry (>30%; 342 cases and 259 controls) did show significant association with SLE (Phigh = 0.018), despite the relatively small sample size.
