Results were available for 22,880 genes. Four genes survived the Benjamini and Hochberg FDR (q<0.05). The gene with the most significant p-value (p=6.24 × 10−6) encodes the NLRP12 protein, which is involved in the regulation of various immune responses and signal transduction. The signal is localized to the 3’ region of the gene (Figure 3). It is expressed across many tissues, with highest levels of expression in the blood (www.genecards.org). The next most significant gene (p=6.44 × 10−6) encodes the glucose transporter SLC2A2, which is involved in carbohydrate metabolism, and has been implicated in noninsulin dependent diabetes mellitus. It is preferentially expressed in the liver and the blood. Multiple SNPs with modest p-values are distributed across SLC2A2, and in the downstream gene EIF5A2 (gene-based p<0.001). The gene EFCAB4B (p=7.14 × 10−6) encodes a calcium ion binding protein and is broadly expressed. The strongest signal (from rs182211455, p=1.89 × 10−5) is intronic. SNPs 5’ to that marker have similar p-values; they are in relatively low LD (r2<0.2) with rs182211455 and therefore may represent independent signals. Finally, TBCE (p=8.52 × 10−6) is
