Since genotype data were not available from the International HapMap Project public database [17] at the time this study was conceived (July 2003), eight single nucleotide polymorphisms (SNPs) in or near the ADLH1A1 locus were selected from the Applied Biosystems SNP database[18]. SNPs were initially chosen to be evenly distributed across ADLH1A1, including one SNP in both the 5' and 3' untranslated regions (UTRs), with an average inter-marker spacing of 10.7 kb.
