The asymptote lines of the analyses in retrospect based on 21 publication years showed that the cumulative synthesis tended towards stability in recent years, in line with the overall results of this meta-analysis. The results of the allelic analysis are shown in Figure 2; and the results of the genotypic analyses are shown in Figures S6 and S7 in Supplement 1. The P(Z) and P(Q) values are shown in Tables S7-S9 in Supplement 1.
