Likewise, Δ9-THC elicited a significant increase in re-entry errors that was blocked by rimonabant, as indicated by a significant interaction between these two drugs, F (1,30) = 15.81, p < 0.01 (Figure 2C). However, systemic administration of Δ9-THC (5.6 mg/kg) produced an increase in maze completion time that was not blocked by intracerebral administration of rimonabant (Figure 2D). A two-way ANOVA revealed no interaction (p = 0.23) or main effect of rimonabant (p = 0.43), but there was a significant main effect of Δ9-THC treatment, F (1,16) = 16.60, p < 0.001. The cannulae placement sites are depicted in Figure 2E and a photomicrograph of the cannulae tracks from a representative rat is shown in Figure 2F.
