represented by the LV. This analysis results in a single map containing a BSR value for each ROI (GMV-EM-PLS). This BSR value then indicates whether GMV of that ROI differs significantly between healthy controls and a single patient group (e.g., patients with L-mTLE). This procedure was repeated for healthy controls and patients with R-mTLE and for the FC-PLS between groups. BSRs for individual ROIs or connections can be found in Table S1.