Given that the evidence base for the treatment of AN remains weak and that no effective medications for its treatment exist,20, 67 advances in our understanding of the underlying biology of the disorder are essential in order to develop novel therapeutics and to reduce the loss of life and diminution of quality of life associated with the disorder. The GCAN/WTCCC3 investigation represents an unprecedented international genetic collaboration in the study of AN, which sets the foundation for further genetic studies.
