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Chunk #25 — Results — Expression studies

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A genome-wide association study of anorexia nervosa.
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We analyzed RNAseq data for whole-brain tissue obtained from 12 different mouse strains(Figure 1). We performed this analysis for 32 mouse orthologues of the 34 human genes identified (Table S4). All 32 genes were expressed in the brain, above an average of 2 FPKM (Fragments Per Kilobase of exon per Million fragments mapped). Specifically, we find extremely high expression levels for Ppp3ca (FPKM value 36.40). Further, we find high expression for Sox2ot, with an FPKM value of 8.02, and similar expression values for Cul3 (10.01) and Ctnna2 (10.79).