proximal, and time-varying) for each parent’s alcohol-related symptoms as well as interactions between these effects of parent alcoholism and study membership. Interactions including study membership were again trimmed when non-significant. Model 2 tested whether there were gender differences in the time-varying effects of parent-alcoholism as a post-hoc analysis. In final models (not tabled), we included interactions between the time-varying and distal effects (Model 3) and between the proximal and distal effects (Model 4) to test whether the effects of alcohol-related symptoms during the study period differentially effected risk for externalizing symptoms among COAs versus controls. Below, we report the combined results.