to 12·26)10·32 (8·88 to 11·63)–7·62 (−8·80 to −6·28)*–5·33 (−5·90 to −4·79)*–12·55 (−13·59 to −11·39)*–12·80 (−13·82 to −11·65)*2Low physical activity18·02 (9·66 to 28·42)18·16 (9·81 to 28·87)18·25 (9·81 to 28·80)0·78 (−28·27 to 39·60)0·51 (−27·42 to 41·11)1·30 (0·94 to 1·72)*15·32 (8·52 to 23·82)15·12 (8·42 to 23·35)15·05 (8·33 to 23·45)–1·28 (−30·22 to 37·56)–0·49 (−28·76 to 41·07)–1·77 (−2·31 to −1·28)*0·07 (−0·32 to 0·38)1Metabolic risks2High fasting plasma glucose2·87 (1·79 to 4·14)3·68 (2·37 to 5·23)3·70 (2·36 to 5·22)28·39 (19·48 to 41·24)*0·60 (−7·76 to 8·12)29·17 (21·33 to 40·03)*2·46 (1·48 to 3·73)3·34 (2·14 to 4·76)3·14 (1·97 to 4·55)35·71 (20·73 to 59·93)*–5·93 (−15·95 to 1·66)27·66 (18·53 to 42·31)*28·77 (21·32 to 39·87)*2High total cholesterol17·43 (13·61 to 21·82)16·87 (13·07 to 21·24)16·75 (12·96 to 21·12)–3·20 (−4·08 to −2·45)*–0·74 (−1·28 to −0·21)*–3·91 (−4·91 to −2·98)*20·14 (16·16 to 24·66)19·30 (15·40 to 23·74)19·05 (15·10 to 23·49)–4·17 (−5·13 to −3·34)*–1·29 (−1·91 to −0·68)*–5·41 (−6·65 to −4·34)*–5·12 (−6·23 to −4·19)*2High systolic blood pressure25·23 (23·60 to 27·13)25·37 (23·68 to 27·32)25·69 (23·99 to 27·69)0·54 (0·18 to 0·91)*1·29 (0·96 to 1·62)*1·83 (1·40 to 2·31)*26·03 (24·45 to 27·80)25·03 (23·53 to 26·77)24·69 (23·20 to 26·38)–3·82 (−4·22 to −3·47)*–1·35 (−1·70 to −0·98)*–5·12 (−5·55 to −4·68)*–1·95 (−2·28 to −1·61)*2High body-mass index5·91 (3·95 to 8·57)7·93 (5·41 to 11·27)9·50 (6·52 to 13·51)34·16 (25·41 to 45·65)*19·82 (15·03 to