A similar pattern of both topographic and integrative connectivity of corticostriatal projections has been demonstrated in the human brain by diffusion magnetic resonance imaging (MRI). These data show a similar overall organization of the different cortical regions and the striatum, providing a strong correlation between monkey anatomical tracing studies and human diffusion MRI studies. 108 Taken together, a coordinated activation of dPFC, dACC, and/or OFC terminals in these subregions could produce a unique combinatorial activation at the specific sites for channeling reward-based incentive drive in selecting between different valued options.
