In both the depressive symptoms and neuroticism GWAS, the heterogeneous phenotypic measures are highly genetically correlated (Supplementary Table 1). As in our subjective well-being analyses, there is substantial inflation of the median test statistics (λGC = 1.168 for depressive symptoms, λGC = 1.317 for neuroticism), but the estimated LD Score intercepts (1.008 and 0.998, respectively) suggest that bias accounts for little or none of the inflation.
