MAGMA tissue expression analysis [17, 18] using GTEx showed significant enrichments in several brain tissues including cerebellum and cortex (Supplementary Figure 5). Although no enrichment was observed via MAGMA gene-set analysis using gene-based p-values of all protein-coding genes, the 152 genes prioritized by positional, expression quantitative trait loci (eQTL), and chromatin interaction mapping were enriched in several gene sets, including ethanol metabolic processes (Supplementary Table 7).
