An additional cluster appears in the left hemisphere located in posterior parts of the left corpus callosum (C4 in Fig. S2) resulting from four contributing foci of four DTI studies [13, 45, 58, 59]. Both analyses were corrected at the cluster level using the FWE correction. This correction resulted in different minimum cluster sizes for the main and the sub-analysis and the diagnostics revealed that the corrected minimum cluster size for the main analysis with 18 studies is at least 824 mm3, whereas the corrected minimum cluster size in the sub-analysis with 11 studies is 688 mm3. The additional cluster of the sub-analysis with a cluster size of 744 mm3 thus only reaches the significance level in the “more liberal” sub-analysis but not in the main analysis.
