To further characterize SNP regulatory potential, we utilized genome-wide SNP genotype (Illumina Human1M–Duo [version 3] and HumanHap650Y [version 3]) and gene expression (Illumina Human 49K Oligo) data made available to the scientific community by the BrainCloud project and dbGaP (accession number phs000417.v2.p1).(Colantuoni et al., 2011) These data enabled us to implicate expression quantitative trait loci (eQTLs) by testing SNP associations with mRNA expression levels. Post-mortem dorsolateral prefrontal cortex samples were retrieved, as previously described (Lipska et al., 2006), from 113 AAs and 110 EAs, ranging in age from 0 to 78 years old, who had no neuropathological or neuropsychiatric diagnoses. Their drug abuse histories are unknown. We did not analyze the fetal samples, given the observed differences in gene expression patterns between fetal and postnatal periods.(Colantuoni et al., 2011)
