We noticed a relationship between patterns of gene expression and the likelihood of behavioral, neurological or related phenotypes in our mutant mouse model database. Mutant mice lacking genes expressed exclusively pre-natally in humans, or genes expressed pre- and post-natally, were more likely to have any behavioral or neurological phenotypes than mutant mice lacking expression of genes expressed primarily in the third trimester or post-natally (p = 1.7 × 10−4) (Supplementary Figure 10).
