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Chunk #4 — Introduction

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Heritability of level of response and association with recent drinking history in nonalcohol-dependent drinkers.
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Studies on the SRE have examined how it compares to other measures of LR such as the Subjective High Assessment Scale (SHAS; Schuckit et al., 1997a; Schuckit et al., 1997b; Eng et al., 2005). While a low LR is indicated in SHAS by a low score SHAS at a particular blood alcohol level, in SRE the same effect is shown by a high score. Due to the retrospective nature of the scale, SRE data may be obtained long after an individual has had their first alcoholic drink. LR observed through these SRE scores could be a function of an individual’s level of alcohol tolerance. The development of tolerance to alcohol over time could result in higher (over-estimated) numbers of drinks reported on the SRE scale (Morean and Corbin, 2008). Nevertheless, studies have found that the SRE is comparable to the level of response measured following an actual alcohol challenge study and can serve as a substitute for measuring level of response in those that cannot consume alcohol such as minors or sober alcoholics (Schuckit et al., 1997a; Schuckit et al., 2009).