In summary, maternal maximum consumption was consistently associated with conduct disorder, ODD in females, any disruptive disorder, and all substance-related outcomes, and the magnitude of associations was relatively unaffected when adjusted for maternal dependence. Dependence itself was somewhat less consistently associated with these same outcome measures. Moreover, only the association with ODD was significant in both cohorts when adjusted for effects of maximum drinks. Partial (adjusted) regression coefficients associated with substance-related outcomes tended toward zero, indicating independence between dependence and offspring outcome once maternal maximum drinks were accounted for.
