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Chunk #27 — RESULTS — Genetic correlations — With what is externalizing genetically correlated?

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A multivariate approach to understanding the genetic overlap between externalizing phenotypes and substance use disorders.
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In Figure 5 and Table S5, we report the correlations of the expanded externalizing factor that emerged from the common factor model with external criteria. Expanded externalizing was significantly genetically correlated with other psychiatric disorders, personality traits, socioeconomic and substance use phenotypes. The strongest correlations were observed with drug exposure (rg = 0.91 [0.06]), prenatal tobacco exposure (rg = 0.77 [0.02]), the Townsend Index reflecting material deprivation (rg = 0.74 [0.04]), suicide attempt (rg = 0.73 [0.05]), antisocial behaviour (rg = 0.69 [0.07]), age of smoking initiation (rg = −0.68 [0.03]) and agreeableness (rg = −0.62 [0.14]).