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Chunk #12 — 2. Materials and Methods — 2.7. Genomic Data and Polygenic Risk Scores (PRS)

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Predicting Alcohol-Related Memory Problems in Older Adults: A Machine Learning Study with Multi-Domain Features.
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The genotyping, imputation, and quality control of COGA genomic data have been described previously [48] and in Section S1.7 of the Supplementary Materials. Table 4 lists the publicly available Genome-wide Association Studies (GWAS) for alcohol use phenotypes, derived from studies including both individuals of European ancestry (EA) and African ancestry (AA), which were used in PRS calculations in this study.