One SNP, rs1824024 located in intron 4 of the CHRM2 gene showed variation that was significantly associated with the P300 trajectory pattern of interest (Figure 3). In the 8–12 year old group, those having two copies of the T nucleotide CHRM2 rs1824024 were 2.60 times more likely (p = 0.032, 95% CI = [1.08, 6.24]) than those with either 1 or 0 copies to exhibit the low and slow developmental P300 trajectory pattern. This relationship did not persist beyond the 8–12 age range. ERP waves by genotype within each age group may be seen in Figure 3.
