paperKB
coga / coga-kb
Help
Sign in

Chunk #47 — 4. Discussion — 4.6. Limitations and Suggestions

Source
Predicting Alcohol-Related Memory Problems in Older Adults: A Machine Learning Study with Multi-Domain Features.
Embedded
yes

Text

and not a psychometric measure; studies that are currently underway are assessing this sample with comprehensive neurocognitive assessments, including memory function, and will be more objective and quantitative; (v) the study does not consider genomic or other trait-related baseline effects that could have influenced the results, and future large-scale studies may consider this aspect in the study design; (vi) for the current sample, recent EEG recordings and neurocognitive assessments including memory function that are missing in the current study, but are underway in our lab, will further add to our predictive modeling; (vii) other specific networks and regions related to memory (e.g., attention and memory networks) are not explored in the current study, although studies are underway in our lab to explore these networks; (viii) PRS for neurocognitive phenotypes, including memory functions, were not included due to lack of availability of multi-ethnic GWAS data. Future studies may attempt to overcome the shortcomings of the study by using larger sample size and stratified analyses, longitudinal designs, multimodal imaging (e.g., fMRI, DTI), and neurocognitive PRS data.