For each sample, for which a forward and reverse sequence file was obtained, a correlation value was calculated between the arcsine of methylation frequency in the forward and reverse directions. Samples with a correlation ≥0.7 (African-American, N = 170; Hispanic, N = 173) were included in the analysis of percent methylation at each CpG site (Table 1). This was the same cut off used in our earlier study of Caucasians (Nielsen et al. 2009).
