Using LDSC, we calculated genetic correlations (rg) between AUDIT and 30 other complex traits or diseases that have been previously associated with AUDIT or alcohol-related phenotypes, for which we had access to summary statistics. We used height as a control. References for the datasets used are identified in Supplementary Table 9. Files were standardized using the steps described in the section above (“Chip-heritability using LD Score Regression”). We did not constrain the intercepts in our analysis because the degree of sample overlap was unknown. We used False Discovery Rate (FDR) to correct for multiple testing (Benjamini & Hochberg 1995).
