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Chunk #14 — RESULTS — Generalization

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Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans.
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There were ten SNPs reported in the NHGRI catalog that are associated with ECG traits in Asian -descent populations. Of these, six SNPs were also genotyped in our study population. None of these SNPs generalized in African Americans with respect to significance and direction of effect, although two of these associations had a consistent direction of effect compared with the original study population.