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Chunk #3 — 1. Introduction — 1.1. Electrophysiological correlates of recognition memory in schizophrenia

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Current source density (CSD) old/new effects during recognition memory for words and faces in schizophrenia and in healthy adults.
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While most ERP research in schizophrenia has relied on P3 amplitude measures during target detection (‘oddball’) tasks (e.g., Ford, 1999), fewer studies have tried to employ paradigms specifically probing left or right hemispheric functions (e.g., Bruder et al., 1999; Kayser et al., 2001) or more complex linguistic and mnemonic processes (e.g., see contributions in this special issue). As one of the most robust findings in ERP memory research, the so-called old/new or episodic memory effect refers to a more positive-going potential for previously-studied and correctly-recognized old than new items (e.g., words, pictures, faces). It begins at about 300 ms post stimulus onset, lasts several hundred milliseconds, and has a left parietal maximum. It overlaps a late P3-like positivity (parietal P600), and is considered an electrophysiological correlate of explicit memory-retrieval processes (e.g., reviews by Johnson, 1995; Allan et al., 1998; Friedman, 2000; Mecklinger, 2000). While this late ERP old/new effect has been linked to conscious recollection, an earlier old/new effect that peaks around 400 ms, lasts about 200 ms, has a mid-frontal maximum, and overlaps a negative ERP deflection (FN400), is