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Chunk #22 — Results — Sample characteristics

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Genome-wide polygenic scores for age at onset of alcohol dependence and association with alcohol-related measures.
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Characteristics of the replication samples, SAGE and OZ-ALC, are presented in Table 1. In both samples, those meeting criteria for AD (NSAGE=1167; NOZ-ALC=1714) were more likely to report an earlier AO-I. They also reported higher Maxdrinks. In general, individuals from SAGE were heavier drinkers and have a greater number of AD-SX than those from OZ-ALC. This is unsurprising given the differences in ascertainment strategies. Modestly, earlier onset of drinking to intoxication and AD was noted in SAGE relative to OZ-ALC. No differences in height were noted across individuals with and without AD or across SAGE and OZ-ALC.