The genotyping rate in the EA sample was 99.7%. After applying several quality control steps (see Methods), 876,476 single nucleotide polymorphisms (SNPs) were analyzed. The sex and age covariates were statistically significant (p<10−15 and p<10−11, respectively) for all screened SNPs (sex was not a covariate for SNPs on the X chromosome). None of the SNPs analyzed met criteria for genome-wide significance (5×10−8; Figure 1, Supplementary Table 1). Ten SNPs had p-values <10−5 (Table 1). Seven of these all fall within known genes: OXTR, FAF1, OPA3, WDR7, SPATA13, EFHA2, and FHIT. The remaining three are located on the X chromosome and are not near any known gene.
