Chunk #28 — Background — Details of data simulation — 2. Areas with LD/unique characteristics

Source

Construction of the model for the Genetic Analysis Workshop 14 simulated data: genotype-phenotype relationships, gene interaction, linkage, association, disequilibrium, and ascertainment effects for a complex phenotype.

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3. Locus D3: B05T4135-B05T4142: There is LD in this region. Disease-carrying haplotypes chosen by similar frequency. 241/1,330 haplotypes carry disease alleles.