Chunk #23 — 3. Results — 3.1 Differences between patients with and without lifetime history of marijuana abuse/dependence

Source

Cannabinoid receptor 1 gene polymorphisms and marijuana misuse interactions on white matter and cognitive deficits in schizophrenia.

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Patients with marijuana abuse/dependence had smaller frontal WM (Adjusted Mean=175.6 versus 180.6cc in patients without marijuana abuse/dependence; F=3.10, p=.07; Figure 2a) and smaller temporal WM volumes (Adjusted Mean=68.6 and 70.0cc respectively; F=5.49, p=.02; Figure 2b). Gray matter, parietal WM and lateral ventricle volumes did not differ significantly between patients with and without marijuana abuse/dependence (F≤2.73, p≥.09).