Allele frequency distributions for CNR1 tSNPs also did not differ significantly between patients with and without marijuana abuse/dependence (Table 2; χ2≤3.19, p≥.07). For rs1049353, G-allele frequency was non-significantly more prevalent among patients with marijuana misuse (77.9% versus 68.8% in patients without marijuana abuse/dependence; p=.07). rs1049353 genotype frequencies across the two comparison groups did not differ significantly either (χ2=3.25, p=.20).
