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Chunk #5 — Frequencies of ADH and ADH Alleles in Indo- and Afro-Trinidadians

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Variations in alcohol-metabolizing enzymes in people of East Indian and African descent from Trinidad and Tobago.
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A third analysis of this island population sought to determine whether ALDH genotypes also affect alcohol dependence and liver function tests in the two major ethnic groups of Trinidad and Tobago (Moore et al. 2007). That study found that none of the subjects carried the protective ALDH2*2 allele, demonstrating that, in contrast to people of East Asian ancestry, this allele is uncommon in people of East Indian ancestry. Moreover, the findings confirm previous data that ALDH2*2 is uncommon in people of African ancestry.