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Chunk #31 — 3. Results — 3.3. Correlations among the Top Significant Variables

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Random Forest Classification of Alcohol Use Disorder Using fMRI Functional Connectivity, Neuropsychological Functioning, and Impulsivity Measures.
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significant correlations with two visual memory scores (i.e., the memory span and total correct scores of the forward condition of the VST), three of them (s1–s4/L.PCC–R.ACC, s2–s4/R.PCC–R.ACC, and s4–s9/R.ACC–L.LTC) showed significant positive correlations (p = 0.05–0.01) and one of the connections (s3–s7/L.ACC–L.PFC) showed a significant negative correlation (p < 0.05) with visual memory scores. Interestingly, the three connections that had positive correlations with visual memory scores also had hypoconnectivity in AUD (Figure 5), whereas the single negatively correlated connection had hyperconnectivity in AUD (Figure 5), thus linking altered FC and poor neuropsychological performance with AUD status. Although similar correlations were observed within each group, these correlations were either less significant or non-significant in the within-group analysis possibly due to a relatively smaller sample size (N = 30).