Cocaine vs. methamphetamine disorders: Within STAA and LTAA, we compared subcortical volumes between subjects with a cocaine disorder to those with a methamphetamine disorder, excluding individuals with both cocaine and methamphetamine disorder. For STAA, there were no differences between those with the two types of disorder (Wilks' λ7,23 = 0.715, p > 0.29). For LTAA, there was a trend toward a significant difference between those with the two types of disorder (Wilks' λ7,20 = 0.548, p = 0.063), with lower volumes for cocaine disorder vs. methamphetamine disorder individuals for the accumbens, hippocampus and thalamus (all p's < 0.05).
