Chunk #28 — Discussion

Source

A common single nucleotide polymorphism A118G of the μ opioid receptor alters its N-glycosylation and protein stability.

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The current studies provided the first experimental evidence that A118G SNP reduced the N-linked glycosylation of the MOPR and, more importantly, the reduction in N-linked glycosylation resulted from this SNP compromised stability of the MOPR protein.