Gene-based analysis was performed with the FUMA implementation of MAGMA. SNPs were mapped to 18,222 protein-coding genes. For each gene, its association with PTSD was determined as the weighted mean χ2 test statistic of SNPs mapped to the gene, where LD patterns were calculated using ancestry appropriate 1KGP reference genotypes. Significance of genes was set at a Bonferroni-corrected threshold of P = 0.05/18,222 = 2.7 × 10−6.
