However, there are important differences between the alcohol challenges and the First 5 SRE score as measures of LR. The SRE reflects global recollections of subjective feelings of intoxication during earlier drinking sessions, while the alcohol challenge measures specific aspects of LR across rising, peak, and falling BACs in a laboratory session and often takes place several years after the onset of drinking. Thus, there are trade offs between the two measures, with the SRE capturing the overall reaction to alcohol in the past, but suffering from errors of retrospection, while the laboratory challenge avoids that problem but results could be impacted by developing tolerance to alcohol. Therefore, while both alcohol challenges and SRE-based LR scores record aspects of reactions to alcohol, they would not be expected to overlap perfectly. Comparisons between SRE measures and alcohol challenges demonstrate correlations that are usually between 0.3 and 0.4, although figures can approach 0.6 when only individuals who are clearly high and low on LR are considered (Schuckit et al., 1997 a, b). Thus, while the correlations between alcohol challenge and SRE-based LR
