LR scores from the SRE are familial, with correlations in first-degree relatives of 0.2 to 0.3 vs. ∼ zero among unrelated individuals (Schuckit et al., 2001, 2005c), and genetic analyses have identified at least one genetic locus potentially linked to both alcohol challenge and SRE LR’s (Schuckit et al., 2001, 2005a). Both measures of LR have also been demonstrated to predict future heavier drinking and alcohol problems (Schuckit et al., 2007, in press, c). The ability of the SRE First 5 score to predict drinking quantities and alcohol problems remained significant after covarying for sex, weight, and for alcohol quantity and problems at the time the SRE was filled out.
