Alcohol dependence and risk for alcoholism in both adults and adolescents is associated with reduced power in event related oscillations (ERO) in a number of different experiments which elicit a P3 or P300 response (a response peak between 300 and 500 ms after the presentation of an infrequent target stimulus) (Jones et al., 2006a; Kamarajan et al., 2006; Rangaswamy et al., 2007; Patrick et al., 2006; Gilmore et al., 2010). ERO power in a task that elicits a P3 response is also associated with a number of SNPs in the CHRM2 gene (Jones et al., 2004, 2006b).
