In this study, we typed 10 SNPs in the CNR1 gene (Table 1). Of these SNPs, 2 (rs2023239 and rs1049353) are synonymous coding SNPs. All the rest are located in the introns of the CNR1 gene (Figure 2A). Except for rs806379, which showed a deviation (P = .01) from the Hardy-Weinberg equilibrium in the VAANX sample, all other SNPs were in the Hardy-Weinberg equilibrium. For both the VAND and VAANX samples, the 10 SNPs were partitioned into 3 LD blocks using the default parameters, and the block boundaries were the same except for the second LD block, which included markers rs6928499, rs806379, and rs2023239 in the VAND sample but included only rs806379 and rs2023239 in the VAANX sample (Figure 2B and C). The overall LD in these 2 samples was similar.
