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Chunk #18 — 3 Results

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Alterations of resting state functional network connectivity in the brain of nicotine and alcohol users.
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Figure 1 shows spatial maps for the set of 39 selected RSNs and Table 2 displays their peak activation coordinates. The RSN groups reflect RSN functions and anatomies following the strategy presented in previous rsFNC studies (Allen et al., 2011). Considered RSN groups are subcortical (SBC), cerebellum (CER), auditory (AUD), sensorimotor (SEN), visual (VIS), salience (SAL), default mode network (DMN), executive control network (ECN) and precuneus (PRE). Spatial overlap with functional brain areas were confirmed by visual comparison with the 90 spatial maps defined by Shirer (Shirer et al., 2012) and by running peak activation coordinates through the meta-analysis software publicly available at http://www.neurosynth.org/. RSNs with peak activations in thalamus and putamen constitute the SBC group. The CER group comprises RSNs with activations on left and right lobule VIIa. The auditory RSN is located at the Heschl’s gyrus. The SEN group covers part of the supplementary motor area (SMA) and large portions of the postcentral gyrus. Fusiform, lingual, superior, middle and inferior occipital gyri are included in the VIS group. One VIS RSN labeled Lingual/Vermis is a complex network that