393453, respectively. The FUSION investigation used 1161 cases and 1174 controls in the discovery phase and 1215 cases and 1258 controls in the replication phase. The Diabetes Genetics Initiative investigation used 1464 cases and 1467 controls in the discovery phase and 5065 cases and 5785 controls in the replication phase. The Wellcome Trust Case control Consortium used 1924 cases and 2938 controls in the discovery phase and 3757 cases and 5346 controls in the replication phase.