Table 1 reports the characteristics of the Yale-Penn and Army STARRS participants investigated in the present study. Although Yale-Penn and Army STARRS present different assessments and characteristics, the data from these cohorts were successfully used to replicate genetic associations identified in studies of SDs and suicidality8,11.Table 1Characteristics of the Yale–Penn and Army STARRS participants investigated in the present study.Yale-Penn, n = 15,557Age, mean (SD)40 (11.8)Sex, Women (%)7187 (46)Self-reported Racial/Ethnic Group, n (%) Native American/American Indian1327 (9) Asian101 (1) Pacific Islander20 (<1) African-American/Black, not of Hispanic origin6027 (39) African-American/Black, of Hispanic origin350 (2) Caucasian/White, not of Hispanic origin6060 (39) Caucasian/White, of Hispanic origin811 (5) Other861 (6)DSM-IV diagnosis, n (%) Alcohol Dependence7481 (48) Cannabis Dependence3897 (25) Cocaine Dependence8662 (56) Nicotine Dependence8219 (52) Opioid Dependence4379 (28)Polysubstance dependence, n (%) One DSM-IV SD diagnosis2023 (13) Two DSM-IV SD diagnoses2942 (22) Three DSM-IV SD diagnoses3345 (22) Four DSM-IV SD diagnoses2419 (16) Five DSM-IV SD diagnoses1004 (6)Suicidality, n (%) Ideation6112 (39) Persistent Ideation1450 (9) Planning2491 (16) Attempt1965 (13)Army STARRS, n = 11,235 Age, mean (SD)21 (5.2) Sex, Women (%)1163 (10) SUDcombined, n (%)2848 (22)Suicidality, n (%) Ideation2299 (20) Planning446 (4) Attempt389 (3)