paperKB
coga / coga-kb
Help
Sign in

Chunk #42 — Discussion

Source
Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.
Embedded
yes

Text

Our meta-analysis findings were generally not more strongly supported by the Narrow analysis, but that sample was also smaller (55% of cases). Narrow cases provided most of the support for such signals in the Broad analysis as ATP6V1B2, GRM7, SP4, PLEKHA7, ITPK1/C14orf109 and regions 10p11.23, 10q11.21, 6p23 and 2q22.1 (Tables 5 and 6 and Supplementary Files). Larger samples of cases with this phenotype might prove useful.