Additional questionnaires (e.g., personality, family history and home environment) were also administered (see 2. Sample and Clinical Data for details). Given the focus on brain‐related phenotypes, COGA collected neurocognitive and neurophysiological measures using EEG and ERP/EROs (Event‐Related Potentials/Event‐Related Oscillations; see 3. Brain Function for details). Blood samples were obtained for genomic data generation and were also immortalized as cell lines in the NIAAA/COGA Sharing repository (see 4. Genetics for details). This rich database has grown over the past three decades via the phased recruitment of additional families or family members and longitudinal follow‐up of participants. For example, the COGA prospective study gathered longitudinal assessments of adolescent and young adult offspring from the families. More recently, recognizing the numerous changes including marriage, divorce, childbirth and career transitions that can significantly impact the course of alcohol use, AUD and remission, COGA has focused on longitudinal data collection of those in mid‐life (30–40s). In addition, because heavy drinking can exacerbate age‐related physical and neurocognitive problems, interact with medications, and cause falls and accidents, especially in older adults, a longitudinal follow‐up of COGA participants aged 50 and older is in progress. A detailed timeline of data collection may be found in 2. Sample and
