Results obtained after deconvolution, i.e., those estimated from latent neural signals, were more in sync with our hypotheses. As we can see from Fig. 8a, FC between the entire thalamus and Layer I across the cortex was significantly greater than the FC between the entire thalamus and layers II–VI (FDR corrected p < 0.05). In addition, FC between the entire thalamus and Layer VI was significantly higher than FC between the entire thalamus and layers II, III, and V. In contrast, the FC between sensory core thalamus (VPL) and layers IV, VI of S1 was significantly stronger than between VPL and layers I, II, III, and V (Fig. 8b).