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Chunk #1 — The genetic architecture of schizophrenia

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Recent genetic findings in schizophrenia and their therapeutic relevance.
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Genetic risk for schizophrenia arises from different forms of DNA sequence variation: the best established are those due to single nucleotide polymorphisms (SNPs) and copy number variants (CNVs). Both act as risk factors; there are no confirmed causal mutations, nor families in which schizophrenia segregates in a Mendelian fashion.