We identified nine general themes from the literature related to facilitators and barriers for researchers to consider when engaging racially/ethnically diverse groups in alcohol genetics research. These were conceptualized along the following continua: curiosity to disinterest; trust to mistrust; understanding to confusion; safety to danger; inclusion to exclusion; sense of connection to disconnection; hope to despair; ease to hassle; and benefit to cost. The nine themes are described in Table 1.