Catalase (CAT) is a heme-containing antioxidant enzyme which can be found in the brain. In normal physiology, CAT converts two H2O2 molecules to water and oxygen only at relatively high H2O2 levels (Nandi et al., 2019). At lower levels, catalase may act as a peroxidase and oxidize a variety of substrates. In the brain, it is responsible for the majority of acetaldehyde production from ethanol oxidation (Rhoads et al., 2012).