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Chunk #11 — 3. Results and Discussion

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Variation in the ADH1B proximal promoter affects expression.
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Data from the different haplotypes were therefore grouped based on the allele of each SNP (e.g., the average activities of all haplotypes with the rs1229982 A allele were compared to those of all haplotypes with C at that position) for analysis. A significant difference in expression was observed for only one SNP, rs1229982 (Table 3). Promoters with the A allele at rs1229982 have, on average, 39% more activity than those with C.